More than likely the coil driver in the PCM is defective. If #1 and #4 are firing then more than likely its a PCM problem. One thing to check is the wiring from PCM to coil. If the wiring has continuity then it's a PCM defect. The PCM only controls the ground to the coil but that's what fires it. A bad coil could have burned the driver circuit in the PCM.
